2186. Risk Factors to predict one-year Community-Acquired Pneumonia in a Low-Middle Income Country: A Prospective Cohort Study

Abstract Background Community-acquired pneumonia (CAP) is the principal cause of mortality due to infectious diseases globally. Some risk factors have been identified for CAP, such as age, smoking, environmental exposures, malnutrition, previous chronic bronchitis/chronic obstructive pulmonary disease (COPD), asthma, functional impairment, poor dental health, and immunosuppressive therapy, among others. However, these studies were conducted in high-income countries patients without comorbid conditions. Therefore, we aimed identify associated with CAP development within a one-year follow-up prospective cohort conditions Colombia. Table 1.Logistic Regression Analysis Methods This adult comorbidities between 2020-and 2022 Bogotá, Univariate analysis multivariate logistic regression model developed variables follow-up. The included p-value<0.20 univariate analysis. Results A total 810 program. Median [IQR] age was 63 [53-62] most common 52.2% [423/810] arterial hypertension, 21.7% [176/810] coronary disease, 19.0% [154/810] congestive heart failure. To date, 678 follow-ups made. Thirty-four died before 6-month follow-up, 46 lost, leaving 598 cumulative incidence 4.3% [26/598] during one year. After adjusting model, main COPD [OR 4.30, 95% CI 1.66-11.11, p< 0.01], antibiotic treatment 4.08, 1.08-15.29, p=0.04] (Table 1). Conclusion Patients history or more than 300% higher developing Robust vaccination programs adults are needed Disclosures All Authors: No reported disclosures.